Active Recombinant Mouse Mmp9 Protein, His-tagged

• Cat.No.: Mmp9-561M
• Product Overview: Recombinant Mouse Mmp9 fused with His tag at N-terminal was expressed in HEK293.

Specification

• Species: Mouse
• Source: HEK293
• Tag: His
• Description: This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme that degrades collagens of type IV, V and XI, and elastin. Mice lacking the encoded protein exhibit an abnormal pattern of skeletal growth plate vascularization and ossification, reduced keratinocyte hyperproliferation at all neoplastic stages, a decreased incidence of invasive tumors, and resistance to experimental autoimmune encephalomyelitis.
• Form: 25 mM TRIS, 10 mM CaCl2, 150 mM NaCl, pH7.5
• Bio-activity: Mouse MMP-9 cleaves the peptide substrate Mca-PLGL(Dpa)AR with a specific activity value higher than 1000 pmol/µg/min after activation.
• Molecular Mass: 81 kDa
• Endotoxin: Less than 1 ng per µg protein as determine by the LAL method.
• Purity: >90%, as determined by Coomassie stained SDS-PAGE.
• Concentration: Protein formulated and vialed at >50 ug/mL in specified buffer

Gene Information

• Gene Name: Mmp9 matrix metallopeptidase 9 [ Mus musculus ]
• Official Symbol: Mmp9
• Synonyms: MMP9; matrix metallopeptidase 9; matrix metalloproteinase-9; GELB; Gel B; gelatinase B; 92kD gelatinase; 92kDa gelatinase; 92 kDa gelatinase; collagenase type IVB; 92kD type IV collagenase; 92kDa type IV collagenase; 92 kDa type IV collagenase; matrix metalloproteinase 9; Clg4b; MMP-9; B/MMP9; AW743869; pro-MMP-9
• Gene ID: 17395
• mRNA Refseq: NM_013599
• Protein Refseq: NP_038627