Active Recombinant Mouse Interleukin 17D

• Cat.No.: Il17d-645M
• Product Overview: RecombinantMouse Il17d protein was expressed in E. coli. Ala25-Arg205.

Specification

• Cat. No.: Il17d-645M
• Description: TheInterleukin 17 (IL-17) family proteins, comprising six members (IL-17, IL-17Bthrough IL-17F), are secreted, structurally related proteins that share a conservedcysteine-knot fold near the C-terminus, but have considerable sequencedivergence at the N-terminus. With the exception of IL-17B, which exists as anon-covalently linked dimer, all IL-17 family members are disulfide-linked dimers.IL17 family proteins are pro-inflammatory cytokines that induce localcytokine production and are involved in the regulation of immune functions.
• Source: E. coli
• Form: Lyophilizedfrom a 0.2 um filtered solution in Acetonitrile and TFA with BSA as a carrierprotein.
• N-terminalSequence: Ala25
• MolecularWeight: 20 kDa (monomer)
• Activity: Measuredby its ability to bind rmIL17-BR/Fc Chimera in a functional ELISA.
• Endotoxin Level: <1.0EU per 1μg of the protein by the LAL method.
• Purity: >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
• Reconstitution: Reconstituteat 100μg/mL in sterile 4 mM HCl containing at least 0.1% human or bovineserum albumin.
• Storage: Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution.
• Tag: Non
• Protein length: 25-205 a.a.

Gene Information

• Gene Name: Il17d interleukin 17D [ Musmusculus ]
• Official Symbol: Il17d
• Synonyms: Il17d; interleukin17D; Il27a; IL-17D; AI462269; interleukin 27A
• Gene ID: 239114
• mRNA Refseq: NM_145837
• Protein Refseq: NP_665836
• UniProt ID: Q8K4C4
• Chromosome Location: 14
• Function: molecular_function