Active Recombinant Mouse ACE2, FLAG-tagged

• Cat.No.: ACE2-69M
• Product Overview: Signal peptide sequence and the extracellular domain of mouse ACE2 (aa 1-740) are fused at the C-terminus to a FLAG-tag.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Flag
• Protein Length: 1-740 a.a.
• Description: ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional receptor for SARS coronavirus.
• Form: Liquid. 0.2μm-filtered solution in PBS.
• Bio-activity: Converts angiotensin I to angiotensin-(1-9).
• Molecular Mass: ~90kDa (SDS-PAGE)
• Purity: ≥90% (SDS-PAGE)
• Stability: Working aliquots are stable for up to 3 months when stored at -20°C.
• Storage: Short Term Storage: +4°C; Long Term Storage: -20°C. After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
• Concentration: 1mg/ml

Gene Information

• Gene Name: Ace2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 [ Mus musculus ]
• Official Symbol: ACE2
• Synonyms: ACE2; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin-converting enzyme 2; ACE-related carboxypeptidase; angiotensin I converting enzyme 2; 2010305L05Rik
• Gene ID: 70008
• mRNA Refseq: NM_001130513
• Protein Refseq: NP_001123985
• Pathway: Protein digestion and absorption, organism-specific biosystem; Protein digestion and absorption, conserved biosystem; Renin-angiotensin system, organism-specific biosystem; Renin-angiotensin system, conserved biosystem
• Function: carboxypeptidase activity; carboxypeptidase activity; endopeptidase activity; glycoprotein binding; hydrolase activity; metal ion binding; metallopeptidase activity; peptidase activity; peptide binding; peptide hormone binding; peptidyl-dipeptidase activity; viral receptor activity