Active Recombinant Human WNT10B Protein

• Cat.No.: WNT10B-112H
• Product Overview: The mature recombinant human Wnt-10b protein containing 389aa (M1-K389) without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Description: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region.
• Bio-activity: Measured in a cell proliferation/survival assay using IEC-18 rat small intestinal epithelial cells. The ED50 for this effect is 0.3-1.2 μg/mL.
• Molecular Mass: 40 kDa
• Product-Related Proteins: 1-389
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: WNT10B Wnt family member 10B [ Homo sapiens (human) ]
• Official Symbol: WNT10B
• Synonyms: WNT10B; Wnt family member 10B; SHFM6; STHAG8; WNT-12; protein Wnt-10b; Names; WNT-10B protein; wingless-type MMTV integration site family, member 10B
• Gene ID: 7480
• mRNA Refseq: NM_003394
• Protein Refseq: NP_003385
• MIM: 601906
• UniProt ID: O00744