Active Recombinant Human VEGFA

• Cat.No.: VEGFA-543H
• Product Overview: Human VEGFA (NP_001020541, 207 a.a.-327 a.a.) partial recombinant protein with His tag expressed in Escherichia coli.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: Vascular endothelial growth factor A (VEGF-A) is a protein that in humans is encoded by the VEGFA gene.
• Sequence: MGSSHHHHHH SSGLVPRGSH MAPMAEGGGQ NHHEVVKFMD VYQRSYCHPI ETLVDIFQEY PDEIEYIFKP SCVPLMRCGG CCNDEGLECV PTEESNITMQ IMRIKPHQGQ HIGEMSFLQH NKCECRPKKD RARQEKCDKP RR
• Theoretical MW (kDa): 16.3
• Form: Liquid
• Preparation Method: E. coli expression system
• Purity: > 95% by SDS-PAGE
• Endotoxin Level: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Activity: The ED50 for this effect is < 4.2 ng/mL. Measured in a cell proliferation assay using NIH-3T3 cell.
• Application: SDS-PAGE
• Storage Buffer: In 20 mM Tris, pH 8.0
• Storage: Store at 4°C for 1-2 weeks. For long term storage store at -20°C or -80°C.
• Unitprot ID: P15692

Gene Information

• Gene Name: VEGFA vascular endothelial growth factor A [ Homo sapiens ]
• Official Symbol: VEGFA
• Synonyms: VPF; VEGF; VEGFA_HUMAN; Vascular permeability factor; VEGF-A; VEGFA; MGC70609; Vegf120; Vegf164; Vegf188; vascular endothelial growth factor A; MGC70609; Vascular endothelial growth factor A precursor; Vascular permeability factor
• Gene ID: 7422
• mRNA Refseq: NM_001025366
• Protein Refseq: NP_001020537
• MIM: 192240
• Chromosome Location: 6p12
• Pathway: Cytokine-cytokine receptor interaction; Focal adhesion; Pancreatic cancer; Renal cell carcinoma; VEGF signaling pathway; mTOR signaling pathway; Hemostasis; Signaling by VEGF.
• Function: cell surface binding ;extracellular matrix binding; growth factor activity; growth factor activity; heparin binding; platelet-derived growth factor receptor binding; protein binding; protein homodimerization activity; vascular endothelial growth factor receptor binding.