Active Recombinant Human TNFRSF17 Protein, Fc-tagged, Alexa Fluor® 488 conjugated

• Cat.No.: TNFRSF17-01H
• Product Overview: Recombinant human Alexa Fluor® 488 conjugated BCMA/TNFRSF17 (Met1-Ala54) protein with a human IgG1 (Pro100-Lys330) Fc tag at C-terminus was expressed in mouse myeloma cell line.

Specification

• Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
• Source: Mouse myeloma cell line
• Species: Human
• Tag: Fc
• Form: Disulfide-linked homodimer
  Labeled with Alexa Fluor® 488 via amines
  Excitation Wavelength: 488 nm
  Emission Wavelength: 515­-545 nm
• Bio-activity: Measured by flow cytometry for its ability to bind anti-Human BCMA/TNFRSF17 Monoclonal Antibody conjugated beads. The concentration of Recombinant human BCMA/TNFRSF17 Chimera Alexa Fluor® 488 that produces 50% of the binding response is 2.00-40.0 ng/mL
• Molecular Mass: 32 kDa
• N-terminal Sequence Analysis: Met1
• Endotoxin: <1.0 EU/μg of the protein by the LAL method.
• Purity: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
• Storage: Protect from light. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  6 months from date of receipt, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after opening.
  3 months, -20 to -70 centigrade under sterile conditions after opening.
• Storage Buffer: Supplied as a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
• Shipping: The product is shipped with dry ice or equivalent.
• Protein length: 1-54 a.a.

Gene Information

• Gene Name: TNFRSF17 TNF receptor superfamily member 17 [ Homo sapiens (human) ]
• Official Symbol: TNFRSF17
• Synonyms: TNFRSF17; TNF receptor superfamily member 17; BCM; BCMA; CD269; TNFRSF13A; tumor necrosis factor receptor superfamily member 17; B cell maturation antigen; B-cell maturation factor; B-cell maturation protein
• Gene ID: 608
• mRNA Refseq: NM_001192
• Protein Refseq: NP_001183
• MIM: 109545
• UniProt ID: Q02223