Active Recombinant Human TNFRSF14 Protein, Fc & Avi-tagged, Biotinylated

• Cat.No.: TNFRSF14-625H
• Product Overview: Biotinylated Human HVEM / TNFRSF14, Fc Tag (HV4-H82F1) is expressed from human HEK293 cells. It contains AA Leu 39 - Val 202 (Accession # NP_003811).

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&Fc
• Protein Length: 39-202 a.a.
• Predicted N Terminal: Leu 39
• Form: Lyophilized from sterile 50 mM tris, 100 mM glycine, pH7.5, 10% Trehalose.
• Bio-activity: Measured by its binding ability in a functional ELISA against immobilized Human TNF-beta (1 μg/well). The linear range is 0.6-10 μg/mL.
• Molecular Mass: This protein carries a human IgG1 Fc fragment at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 45.8 kDa. The protein migrates as 55-66 kDa on a SDS-PAGE gel under reducing condition due to glycosylation.
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: TNFRSF14 tumor necrosis factor receptor superfamily, member 14 [ Homo sapiens ]
• Official Symbol: TNFRSF14
• Synonyms: TNFRSF14; tumor necrosis factor receptor superfamily, member 14; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); tumor necrosis factor receptor superfamily member 14; ATAR; CD270; herpesvirus entry mediator; HVEA; HVEM; LIGHTR; TR2; CD40-like protein; herpesvirus entry mediator A; herpes virus entry mediator A; tumor necrosis factor receptor-like 2; tumor necrosis factor receptor-like gene2
• Gene ID: 8764
• mRNA Refseq: NM_003820
• Protein Refseq: NP_003811
• MIM: 602746
• UniProt ID: Q92956
• Chromosome Location: 1p36.32
• Pathway: Adaptive Immune System, organism-specific biosystem; Costimulation by the CD28 family, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem; Immune System, organism-specific biosystem
• Function: protein binding; receptor activity; tumor necrosis factor-activated receptor activity