Active Recombinant Human TNFRSF13C, Fc-tagged, Biotinylated

• Cat.No.: TNFRSF13C-551H
• Product Overview: The recombinant human BAFFR-Fc fusion is expressed as a 300 amino acid protein consisting of Arg2 - Gly76 region of BAFFR (UniProt accession #Q96RJ3) and a C-terminal Fc from human IgG1, which exists as a dimer/tetramer/oligomer under non-reducing conditions

Specification

• Species: Human
• Source: Human Cells
• Tag: Fc
• Protein Length: 2-76 a.a.
• Form: Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
• Bio-activity: Binds to its ligand BAFF. Inhibits BAFF-mediated signaling activities including NF-κB activation and proliferation of anti--IgM co-stimulated B cells.
• Molecular Mass: Calculated molecular mass (kDa): 33; Estimated by SDS-PAGE under reducing condition (kDa): 40-45
• Endotoxin: <0.1 eu per 1 μg of purified recombinant protein determined by the
• Purity: >95% judged by SDS-PAGE under reducing condition
• Storage: The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: TNFRSF13C tumor necrosis factor receptor superfamily, member 13C [ Homo sapiens ]
• Official Symbol: TNFRSF13C
• Synonyms: TNFRSF13C; tumor necrosis factor receptor superfamily, member 13C; tumor necrosis factor receptor superfamily member 13C; BAFFR; CD268; BAFF receptor; BLyS receptor 3; B cell-activating factor receptor; B-cell-activating factor receptor; CVID4; BAFF-R; BROMIX; prolixin; MGC138235
• Gene ID: 115650
• mRNA Refseq: NM_052945
• Protein Refseq: NP_443177
• MIM: 606269
• UniProt ID: Q96RJ3
• Chromosome Location: 22q13.1-q13.3
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Intestinal immune network for IgA production, organism-specific biosystem; Intestinal immune network for IgA production, conserved biosystem; Primary immunodeficiency, organism-specific biosystem
• Function: receptor activity