Active Recombinant Human SIGLEC5 Protein, Fc Chimera

• Cat.No.: SIGLEC5-941H
• Product Overview: Recombinant Human SIGLEC5 (Accession # O15389), fused with , was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: Fc
• Predicted N Terminal: Glu17
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by the ability of the immobilized protein to support the adhesion of human red blood cells. Kelm, S. et al. (1994) Current Biology 4:965.The ED50 for this effect is typically 1 - 4 µg/mL.
• Molecular Mass: Recombinant Human SIGLEC5, Fc Chimera has a calculated MW of 73 kDa (monomer). In SDS-PAGE migrates as 100-110 kDa, reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: SIGLEC5 sialic acid binding Ig-like lectin 5 [ Homo sapiens ]
• Official Symbol: SIGLEC5
• Synonyms: SIGLEC5; sialic acid binding Ig-like lectin 5; CD33L2; sialic acid-binding Ig-like lectin 5; CD170; OB BP2; SIGLEC 5; CD33 antigen-like 2; OB-binding protein 2; obesity-binding protein 2; sialic acid-binding immunoglobulin-like lectin 5; OBBP2; OB-BP2; SIGLEC-5
• Gene ID: 8778
• mRNA Refseq: NM_003830
• Protein Refseq: NP_003821
• MIM: 604200
• UniProt ID: O15389
• Chromosome Location: 19q13.41