Active Recombinant Human SENP2, GST-tagged

• Cat.No.: SENP2-687H
• Product Overview: Recombinant Human SENP2 is produced inE. coliwith a GST tag.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Description: SENP2 was discovered both through its homology to other SUMO proteases. When overexpressed in tissue culture cells or underin vitro conditions, the murine SENP2 homologue (Smt3IP2) cleaves conjugates of SUMO-1, SUMO-2, and SUMO-3. full length human SENP2 associates with nuclear pores in a manner similar to Ulp1 in yeast. This association occurs exclusively with the nuclear face of the pore and requires sequences near the N-terminus of SENP2.
• Activity: This fragment has full de-SUMOylating activity.
• Storage: -80°C.

Gene Information

• Gene Name: SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 [ Homo sapiens ]
• Synonyms: SENP2; SUMO1/sentrin/SMT3 specific peptidase 2; AXAM2; SMT3IP2; KIAA1331; DKFZp762A2316; sentrin-specific protease 2; SMT3-specific isopeptidase 2; sentrin/SUMO-specific protease SENP2; SUMO1/sentrin/SMT3 specific protease 2; EC 3.4.22.-
• Gene ID: 59343
• mRNA Refseq: NM_021627
• Protein Refseq: NP_067640
• MIM: 608261
• UniProt ID: Q9HC62
• Chromosome Location: 3q27.2
• Pathway: Wnt signaling pathway
• Function: SUMO-specific protease activity; cysteine-type peptidase activity; peptidase activity; protein binding