Active Recombinant Human SEMA5A, HIgG1 Fc-tagged
| Cat.No. : | SMA5A-3512H |
| Product Overview : | The extracellular domain of human SEMA5A (AAI15697.1) (Glu23-Thr765) is fused to the N-terminus of the Fc region of human IgG1was expressed in CHO cell |
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| Description : | This gene belongs to the semaphorin gene family that encodes membrane proteins containing a semaphorin domain andseveral thrombospondin type-1 repeats. Members of this family are involved in axonal guidance during neuraldevelopment. This gene has been implicated as an autism susceptibility gene |
| Source : | CHO cell |
| Species : | Human |
| Tag : | HIgG1 Fc-tagged |
| Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
| Bio-activity : | Measured by its ability to inhibit proliferation. |
| Molecular Mass : | 110KDa (monomer) |
| AA Sequence : | Glu23-Thr765 |
| Endotoxin : | <0.06 eu/μg="" as="" determined="" by="" lal="" test.=""> |
| Purity : | >98%, by SDS-PAGE under reducing conditions. |
| Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
| Warning : | Avoid freeze/thaw cycles. |
| Protein length : | 23-765 a.a. |
| Gene Name | SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A [ Homo sapiens ] |
| Official Symbol | SEMA5A |
| Synonyms | SEMA5A; sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A; SEMAF; semaphorin-5A; semF; sema F; semaphorin F; semaphorin-F; FLJ12815; |
| Gene ID | 9037 |
| mRNA Refseq | NM_003966 |
| Protein Refseq | NP_003957 |
| MIM | 609297 |
| UniProt ID | Q13591 |
| Chromosome Location | 5p15.2 |
| Pathway | Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Other semaphorin interactions, organism-specific biosystem; Semaphorin interactions, organism-specific biosystem; |
| Function | axon guidance receptor activity; receptor activity; |
Not For Human Consumption!
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