Active Recombinant Human RAB31, Member RAS Oncogene Family, GST-tagged

• Cat.No.: RAB31-1108H

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Description: Rab31 is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. The small Rab31 GTPase is associated with early endosomes and trans Golgi. It regulates biosynthetic pathways from endosomes to Golgi. It plays an important role in phagosome maturation. The GST-Tag facilitates the protein's application in typical GST pull-down assays.
• Usage: For in vitro use only.
• Form: Liquid. Supplied in 50 mM Tris-HCl pH 8.0, 100 mM NaCl, 10 mM MgCl2, 10 μM GDP and 2 mM mercaptoethanol.
• Activity: 100 pmol of protein can bind > 80 pmol of GDP.
• Purity: ≥ 90% by SDS-PAGE.
• Storage: Quality guaranteed for 12 months. Store at -80℃. Avoid freeze / thaw cycles.

Gene Information

• Gene Name: RAB31 RAB31, member RAS oncogene family [ Homo sapiens ]
• Synonyms: RAB31; RAB31, member RAS oncogene family; Rab22B; Ras-related protein Rab-31; Rab-22B; RAB22B
• Gene ID: 11031
• mRNA Refseq: NM_006868
• Protein Refseq: NP_006859
• MIM: 605694
• UniProt ID: Q13636
• Chromosome Location: 18p11.3
• Pathway: Endocytosis
• Function: GTP binding; GTPase activity; nucleotide binding