Active Recombinant Human PTX3 Protein, His-tagged

• Cat.No.: PTX3-02H
• Product Overview: Recombinant Human PTX3 Protein (Glu 18-Ser 381) with a C-terminal 6-His tag was expressed in Chinese Hamster Ovary cell line.

Specification

• Species: Human
• Source: CHO
• Tag: His
• Protein Length: 18-381
• Description: This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions.
• Bio-activity: Measured by its binding ability in a functional ELISA. When Human C1q is immobilized at 5 μg/mL (100 μL/well), Recombinant Human Pentraxin 3/TSF-14 His-tag binds with an ED50 of 0.5-4 μg/mL.
• Molecular Mass: Predicted Molecular Mass: 41 kDa
  SDS-PAGE: 38-55 kDa, under reducing conditions
• N-terminal Sequence Analysis: Glu18
• Endotoxin: <0.10 EU/μg of the protein by the LAL method.
• Purity: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Shipping: The product is shipped at ambient temperature.

Gene Information

• Gene Name: PTX3 pentraxin 3 [ Homo sapiens (human) ]
• Official Symbol: PTX3
• Synonyms: PTX3; pentraxin 3; TSG-14; TNFAIP5
• Gene ID: 5806
• mRNA Refseq: NM_002852
• Protein Refseq: NP_002843
• MIM: 602492
• UniProt ID: P26022