Active Recombinant Human PADI4, His-tagged
Cat.No. : | PADI4-380H |
Product Overview : | Recombinant Human PADI4 (Ala2-Pro663) fused with an N-terminal 11 kDa fusion protein, a thrombin cleavage linker and 6His tag at Cterminal, was expressed in E. coli. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Protein Length : | 2-663 a.a. |
Description : | This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. |
Predicted N Terminal : | Inconclusive result, Met predicted. Protein identity confirmed by MS analysis of tryptic fragments |
Formulation : | Supplied as a 0.2 µm filtered solution in Sodium Acetate, NaCl, DTT, EDTA and Glycerol. |
Bio-activity : | Measured by its ability to catalyze the deimination of benzoyl-arginine ethyl ester. The specific activity is >1000 pmol/min/µg, as measured under the described conditions. |
Molecular Mass : | Predicted Molecular Mass: 87 kDa SDS-PAGE: 75-85 kDa, reducing conditions |
Endotoxin : | < 1.0 EU per 1 μg of the protein by the LAL method. |
Purity : | >90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 µg per lane. |
Storage : | Avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening. |
Gene Name | PADI4 peptidyl arginine deiminase, type IV [ Homo sapiens (human) ] |
Official Symbol | PADI4 |
Synonyms | PADI4; PAD; PAD4; PDI4; PDI5; PADI5; peptidyl arginine deiminase, type IV; protein-arginine deiminase type-4; HL-60 PAD; PADI-H protein; protein-arginine deiminase type IV; peptidyl arginine deiminase, type V; EC 3.5.3.15 |
Gene ID | 23569 |
mRNA Refseq | NM_012387 |
Protein Refseq | NP_036519 |
MIM | 605347 |
UniProt ID | Q9UM07 |
Chromosome Location | 1p36.13 |
Pathway | protein citrullination |
Function | calcium ion binding; protein-arginine deiminase activity |
◆ Recombinant Proteins | ||
PADI4-293H | Recombinant Human PADI4 Protein, His-tagged | +Inquiry |
PADI4-313H | Recombinant Human PADI4 Protein, His-tagged | +Inquiry |
PADI4-1652C | Recombinant Cynomolgus PADI4 protein, His-tagged | +Inquiry |
PADI4-30160H | Recombinant Human PADI4 protein, GST-tagged | +Inquiry |
Padi4-11M | Recombinant Mouse Padi4 Protein, His-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
PADI4-630HCL | Recombinant Human PADI4 cell lysate | +Inquiry |
Not For Human Consumption!
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