Active Recombinant Human NNMT protein, GST-tagged

Cat.No. : NNMT-193H
Product Overview : Recombinant Human NNMT fused with GST tag at N-terminal was expressed in Insect cells.
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Description : Nicotinamide N-methyltransferase (NNMT) is expressed predominantly in the liver, and mediates the N-methylation of nicotinamide and other pyridines. The activity of NNMT is involved in drug and xenobiotic toxicity. NNMT has also been identified as serum tumor marker for colorectal cancer, as well as potential marker in urine-based diagnostic test for bladder cancer.
Source : Insect cells
Species : Human
Tag : GST
Form : 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity : 220 nmol/min/mg
Molecular Mass : 54 kDa
Purity : >95%
Applications : Methyltransferase Assay
Stability : 1 year at -70 centigrade from the date of shipment
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1μg/μl
Gene Name NNMT nicotinamide N-methyltransferase [ Homo sapiens ]
Official Symbol NNMT
Synonyms NNMT; nicotinamide N-methyltransferase;
Gene ID 4837
mRNA Refseq NM_006169
Protein Refseq NP_006160
MIM 600008
UniProt ID P40261
Chromosome Location 11q23.1
Pathway Biological oxidations, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Methylation, organism-specific biosystem; Nicotinate and nicotinamide metabolism, organism-specific biosystem; Nicotinate and nicotinamide metabolism, conserved biosystem; Phase II conjugation, organism-specific biosystem;
Function methyltransferase activity; nicotinamide N-methyltransferase activity; transferase activity;

Not For Human Consumption!

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