Active Recombinant Human/Mouse/Rat INHBA Protein (Gly311-Ser426), GMP Grade
Cat.No. : | INHBA-09HG |
Product Overview : | GMP recombinant human/Mouse/Rat Activin A protein (Gly311-Ser426) without tag was expressed in Chinese Hamster Ovary cell line and manufactured and tested under cGMP guidelines. |
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Species : | Human/Mouse/Rat |
Source : | CHO |
Protein Length : | Gly311-Ser426 |
Description : | This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients. |
Form : | Disulfide-linked homodimer |
Bio-activity : | Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. The ED50 for this effect is 0.2-1.2 ng/mL. The specific activity of Recombinant Human/Mouse/Rat Activin A is >1000 units/mg, which is calibrated against the human Activin A WHO reference standard. |
Molecular Mass : | Predicted Molecular Mass: 13 kDa (monomer) SDS-PAGE: 14 kDa, reducing conditions; 24 kDa, non-reducing conditions |
N-terminal Sequence Analysis : | Gly311-Leu-Glu-(Cys)-Asp-Gly-Lys-Val-Asn-Ile |
Endotoxin : | <0.10 EU/ μg of the protein by the LAL method. |
Purity : | >97%, by SDS-PAGE with silver staining. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. A minimum of 12 months when stored at ≤ -20 centigrade as supplied. Refer to lot specific COA for the Use by Date. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, ≤ -20 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA. |
Reconstitution : | Reconstitute at 100-500 μg/mL in sterile 4 mM HCl. |
Shipping : | The product is shipped with polar packs. |
Gene Name | INHBA inhibin, beta A [ Homo sapiens ] |
Official Symbol | INHBA |
Synonyms | INHBA; inhibin, beta A; inhibin, beta A (activin A, activin AB alpha polypeptide); inhibin beta A chain; Inhibin, beta-1; activin beta-A chain; FSH-releasing protein; erythroid differentiation factor; erythroid differentiation protein; follicle-stimulating hormone-releasing protein; EDF; FRP; |
Gene ID | 3624 |
mRNA Refseq | NM_002192 |
Protein Refseq | NP_002183 |
MIM | 147290 |
UniProt ID | P08476 |
◆ Recombinant Proteins | ||
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INHBA-3113H | Recombinant Human INHBA Protein (Met1-Ser426), N-His tagged | +Inquiry |
INHBA-525H | Recombinant Human Activin INHBA protein, low endotoxin | +Inquiry |
INHBA-3065R | Recombinant Rat INHBA Protein | +Inquiry |
◆ Cell & Tissue Lysates | ||
INHBA-2078MCL | Recombinant Mouse INHBA cell lysate | +Inquiry |
Not For Human Consumption!
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