Active Recombinant Human LTBR, Fc-tagged, Biotinylated

Source :	Human cells
Species :	Human
Tag :	Fc
Form :	Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
Bio-activity :	Binds to its ligand LIGHT and lymphotoxin-α1/β2. Inhibits LIGHT/lymphotoxin-α1/β2-mediated biological activities including NF-κB activation and cytotoxicity.
Molecular Mass :	Calculated molecular mass (kDa): 46.8; Estimated by SDS-PAGE under reducing condition (kDa): 55-60
Endotoxin :	<0.1 eu="" per="" 1="" μg="" of="" purified="" recombinant="" protein="" determined="" by="" the="" lal="">
Purity :	>95% judged by SDS-PAGE under reducing condition
Storage :	The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
Protein length :	31-234 a.a.

Gene Name	LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) [ Homo sapiens ]
Official Symbol	LTBR
Synonyms	LTBR; lymphotoxin beta receptor (TNFR superfamily, member 3); D12S370; tumor necrosis factor receptor superfamily member 3; TNF R III; TNFCR; TNFR RP; TNFR2 RP; TNFRSF3; TNF-RIII; TNFR-III; lymphotoxin B receptor; lymphotoxin-beta receptor; TNFR superfamily, member 3; tumor necrosis factor C receptor; tumor necrosis factor receptor type III; tumor necrosis factor receptor 2-related protein; tumor necrosis factor receptor superfamily, member 3; CD18; TNFR-RP; TNFR2-RP; LT-BETA-R; TNF-R-III;
Gene ID	4055
mRNA Refseq	NM_002342
Protein Refseq	NP_002333
MIM	600979
UniProt ID	P36941
Chromosome Location	12p13
Pathway	Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Intestinal immune network for IgA production, organism-specific biosystem; Intestinal immune network for IgA production, conserved biosystem;
Function	identical protein binding; protein binding; receptor activity;

COA

Cat.No. :	LTBR-636H
Product Overview :	The recombinant human LTβR-Fc fusion is expressed as a 420 amino acid protein consisting of Gln31 - Thr234 region of LTβR (UniProt accession #P36941) and a C-terminal Fc from human IgG1, which exists as a dimer/tetramer/oligomer under non-reducing conditions.