Active Recombinant Human INHBA protein
Cat.No. : | INHBA-267H |
Product Overview : | Recombinant Human INHBA was expressed in Insect cells. |
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Species : | Human |
Source : | Insect Cells |
Tag : | Non |
Description : | Activin A is a TGF beta family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in post-menopausal woman have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF beta antagonist, Follistatin. |
Form : | Lyophilized from 10 mM Citric Acid pH 3.0. Reconstitute in water to a concentration of 0.5 mg/ml. Do not vortex. |
Bio-activity : | The ED50 as determined by its ability to inhibit the proliferation of Mouse MPC-11 cells is 2 ng/ml, corresponding to a specific activity of 5 x 10^5 units/mg. |
Molecular Mass : | 26 kDa |
AA Sequence : | GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS. |
Endotoxin : | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
Purity : | >95% pure by SDS PAGE and HPLC |
Notes : | Small volumes of Activin A recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice. |
Storage : | Store at 4 centigrade until reconstitution. Following reconstitution aliquot and freeze at -20 centigrade for long term storage. Avoid repeated freeze/thaw cycles. |
Gene Name | INHBA inhibin, beta A [ Homo sapiens ] |
Official Symbol | INHBA |
Synonyms | INHBA; inhibin, beta A; inhibin, beta A (activin A, activin AB alpha polypeptide); inhibin beta A chain; Inhibin, beta-1; activin beta-A chain; FSH-releasing protein; erythroid differentiation factor; erythroid differentiation protein; follicle-stimulating hormone-releasing protein; EDF; FRP; |
Gene ID | 3624 |
mRNA Refseq | NM_002192 |
Protein Refseq | NP_002183 |
MIM | 147290 |
UniProt ID | P08476 |
Chromosome Location | 7p15-p13 |
Pathway | ALK1 signaling events, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Glycoprotein hormones, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Peptide hormone biosynthesis, organism-specific biosystem; |
Function | cytokine activity; follistatin binding; growth factor activity; hormone activity; identical protein binding; protein binding; protein heterodimerization activity; type II activin receptor binding; |
◆ Recombinant Proteins | ||
INHBA-276H | Recombinant Human Inhibin A, His-tagged | +Inquiry |
INHBA-5644H | Recombinant Human/Mouse/Rat INHBA protein, GMP Grade, Animal-Free, For Organoid Culture | +Inquiry |
INHBA-64H | Recombinant Human INHBA | +Inquiry |
INHBA-5059H | Recombinant Human Inhibin, Beta A, His-tagged | +Inquiry |
INHBA-32H | Recombinant Human INHBA Protein (AA 21-426), N-GFP/His-Tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
INHBA-2078MCL | Recombinant Mouse INHBA cell lysate | +Inquiry |
Not For Human Consumption!
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