Active Recombinant Human IL8 (23-99aa)

• Cat.No.: IL8-361H
• Product Overview: Human IL8 (P10145, 23 a.a. - 99 a.a.) partial recombinant protein expressed in Escherichia coli.

Specification

• Cat. No.: IL8-361H
• Description: Interleukin-8 (IL8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 protein is encoded by the IL8 gene.
• Sequence: AVLPRSAK ELRCQCIKTY SKPFHPKFIK ELRVIESGPH CANTEIIVKL SDGRELCLDP KENWVQRVVE KFLKRAENS
• Theoretical MW (kDa): 9
• Form: Lyophilized
• Preparation Method: E. coli expression system
• Purity: > 95% by SDS-PAGE and HPLC
• Endotoxin Level: < 0.1 ng/ug (1 EU/ug)
• Activity: Activity was determined by the ability to chemoattract human pheripheral blood monocytes was found to be in the range of 25.0-100.0 ng/mL.
• Application: SDS-PAGE
• Storage Buffer: Lyophilized from PBS, pH 7.0
• Storage: Store at -20°C on dry atmosphere. After reconstitution with deionized water, store at -20°C. Aliquot to avoid repeated freezing and thawing.
• Unitprot ID: P10145
• Tag: Non
• Protein length: 23-99 a.a.

Gene Information

• Gene Name: IL8 interleukin 8 [ Homo sapiens ]
• Official Symbol: IL8
• Synonyms: IL8; 3-10C; AMCF-I; CXCL8; Emoctakin; GCP-1; GCP1; IL-8; K60; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8; TSG-1; b-ENAP; emoctakin; C-X-C motif chemokine 8; Granulocyte chemotactic protein 1; Monocyte-derived neutrophil chemotactic factor; Monocyte-derived neutrophil-activating peptide; Neutrophil-activating protein 1; Protein 3-10C; T cell chemotactic factor; T-cell chemotactic factor; beta-thromboglobulin-like protein; chemokine (C-X-C motif) ligand 8; interleukin 8; lymphocyte-derived neutrophil-activating factor; neutrophil-activating peptide 1; small inducible cytokine subfamily B, member 8; Interleukin-8
• Gene ID: 3576
• mRNA Refseq: NM_000584
• Protein Refseq: NP_000575
• MIM: 146930
• Chromosome Location: 4q13-q21
• Pathway: Cytokine-cytokine receptor interaction; Epithelial cell signaling in Helicobacter pylori infection; Leukocyte transendothelial migration; Toll-like receptor signaling pathway; Signaling by GPCR
• Function: chemokine activity; interleukin-8 receptor binding; protein binding