Active Recombinant Human IL22RA2 Protein, Fc Chimera

• Cat.No.: IL22RA2-870H
• Product Overview: Recombinant Human IL22RA2 (Accession # NP_851826), fused with , was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: Fc
• Predicted N Terminal: Thr22
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to inhibit IL-22-induced IL-10 secretion by COLO 205 human colorectal adenocarcinoma cells.The ED50 for this effect is typically 4-20 ng/mL in the presence of 1 ng/mL of Recombinant Human IL-22.
• Molecular Mass: Recombinant Human IL22RA2, Fc Chimera has a calculated MW of 51.3 kDa (monomer). In SDS-PAGE migrates as 75-80 kDa, reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
• Reconstitution: Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.

Gene Information

• Gene Name: IL22RA2 interleukin 22 receptor, alpha 2 [ Homo sapiens ]
• Official Symbol: IL22RA2
• Synonyms: IL22RA2; interleukin 22 receptor, alpha 2; interleukin-22 receptor subunit alpha-2; CRF2 S1; IL 22BP; zcytoR16; IL-22R-alpha-2; class II cytokine receptor; IL-22 receptor subunit alpha-2; interleukin 22-binding protein; interleukin-22-binding protein; cytokine receptor class-II member 10; cytokine receptor family 2 member 10; cytokine receptor family type 2, soluble 1; CRF2X; CRF2-10; CRF2-S1; IL-22BP; IL-22RA2; MGC150509; MGC150510
• Gene ID: 116379
• mRNA Refseq: NM_052962
• Protein Refseq: NP_443194
• MIM: 606648
• UniProt ID: Q969J5
• Chromosome Location: 6q24.1-q24.2