Active Recombinant Human IL22RA1, HIgG1 Fc-tagged
| Cat.No. : | IL22RA1-791H |
| Product Overview : | The extracellular domain of human IL-22RA1 (AAH29273.1)(Pro18-Thr228) is fused to the N-terminus of the Fc region of human IgG1was expressed in CHO cell. |
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| Description : | The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be areceptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein andinterleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10(IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in thechromosomal region 1p36. |
| Source : | CHO cell |
| Species : | Human |
| Tag : | HIgG1 Fc-tagged |
| Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
| Bio-activity : | Measured by its ability to inhibit IL-22-induced IL-10 secretion by COLO 205 human colorectal adenocarcinoma cells. |
| Molecular Mass : | 50KDa (monomer) |
| AA Sequence : | Pro18-Thr228 |
| Endotoxin : | <0.06 eu/μg="" as="" determined="" by="" lal="" test.=""> |
| Purity : | >98%, by SDS-PAGE under reducing conditions. |
| Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
| Warning : | Avoid freeze/thaw cycles. |
| Protein length : | 18-228 a.a. |
| Gene Name | IL22RA1 interleukin 22 receptor, alpha 1 [ Homo sapiens ] |
| Official Symbol | IL22RA1 |
| Synonyms | IL22RA1; interleukin 22 receptor, alpha 1; IL22R, interleukin 22 receptor; interleukin-22 receptor subunit alpha-1; CRF2 9; IL-22RA1; zcytoR11; IL-22R-alpha-1; IL-22 receptor subunit alpha-1; cytokine receptor class-II member 9; cytokine receptor family 2 member 9; IL22R; CRF2-9; IL22R1; |
| Gene ID | 58985 |
| mRNA Refseq | NM_021258 |
| Protein Refseq | NP_067081 |
| MIM | 605457 |
| UniProt ID | Q8N6P7 |
| Chromosome Location | 1p36.11 |
| Pathway | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; |
| Function | interferon receptor activity; receptor activity; |
Not For Human Consumption!
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