Active Recombinant Human IL17RB Protein, Fc-tagged
Cat.No. : | IL17RB-483H |
Product Overview : | Recombinant human IL17BR (NP_061195.2) (Met1-Gly289) was expressed with the Fc region of human IgG1 at the C-terminus. |
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Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Predicted N Terminal : | Arg 18 |
Form : | Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol. |
Bio-activity : | 1. Measured by its binding ability in a functional ELISA.2. Immobilized human IL17BR-Fc at 10μg/mL (100μL/well) can bind biotinylated human Fc-IL25 (Cat:10096-H01H).The EC50 of human Fc-IL25 (Cat:10096-H01H) is 4.5-10.4ng/mL. |
Molecular Mass : | The recombinant human IL17BR/Fc is a disulfide-linked homodimer. The reduced monomer comprises 513 amino acids and has a predicted molecular mass of 56.9 kDa. The apparent molecular mass of the protein is approximately 67 kDa in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >85 % as determined by SDS-PAGE. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Protein length : | 1-289 a.a. |
Gene Name | IL17RB interleukin 17 receptor B [ Homo sapiens ] |
Official Symbol | IL17RB |
Synonyms | IL17RB; interleukin 17 receptor B; IL17BR, interleukin 17B receptor; interleukin-17 receptor B; CRL4; EVI27; IL17RH1; IL-17RB; IL-17Rh1; IL-17B receptor; IL-17 receptor B; cytokine receptor CRL4; IL-17 receptor homolog 1; cytokine receptor-like 4; interleukin 17B receptor; interleukin-17B receptor; interleukin 17 receptor homolog 1; IL17BR; MGC5245; |
Gene ID | 55540 |
mRNA Refseq | NM_018725 |
Protein Refseq | NP_061195 |
MIM | 605458 |
UniProt ID | Q9NRM6 |
Chromosome Location | 3p21.1 |
Pathway | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
Not For Human Consumption!
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