Active Recombinant Human ICAM1, HIgG1 Fc-tagged
| Cat.No. : | ICAM1-101H |
| Product Overview : | The extracellular domain of human CD54 (AAH15969.1) (Met1-Glu480)(Gln348Lys) is fused to the N-terminus of the Fc region of human IgG1 was expressed in CHO cell. |
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| Description : | This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor |
| Source : | CHO cells |
| Species : | Human |
| Tag : | HIgG1 Fc-tagged |
| Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
| Bio-activity : | Measured by the ability of the immobilized protein to support the adhesion of PMA-stimulated HSB2 human peripheral blood acute lymphoblastic leukemia cells. |
| AA Sequence : | (Met1-Glu480)(Gln348Lys) |
| Endotoxin : | <0.06 eu/μg="" as="" determined="" by="" lal="" test.=""> |
| Purity : | >98%, by SDS-PAGE under reducing conditions. |
| Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
| Warning : | Avoid freeze/thaw cycles. |
| Protein length : | 1-480 a.a. |
| Gene Name | ICAM1 intercellular adhesion molecule 1 [ Homo sapiens ] |
| Official Symbol | ICAM1 |
| Synonyms | ICAM1; intercellular adhesion molecule 1; BB2; CD54; human rhinovirus receptor; ICAM-1; cell surface glycoprotein P3.58; major group rhinovirus receptor; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; P3.58; |
| Gene ID | 3383 |
| mRNA Refseq | NM_000201 |
| Protein Refseq | NP_000192 |
| MIM | 147840 |
| UniProt ID | P05362 |
| Chromosome Location | 19p13.3-p13.2 |
| Pathway | Adaptive Immune System, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Glucocorticoid receptor regulatory network, organism-specific biosystem; |
| Function | cell surface binding; integrin binding; protein binding; receptor activity; transmembrane signaling receptor activity; |
Not For Human Consumption!
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