Active Recombinant Human Hepatitis A Virus Cellular Receptor 2, HIgG1 Fc-tagged

• Cat.No.: HAVCR2-218H
• Product Overview: The extracellular domain of mouse Tim-3(AAI06852.1) (Ser21-Thr189) is fused to the N-terminus of the Fc region of human IgG1.

Specification

• Species: Human
• Source: CHO
• Tag: Fc
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Immobilized Recombinant Human Galectin 9 at 500 ng/mL can bind Tim-3 (mouse):Fc (human) (rec.) with an apparent KD<10 nm.="" optimal="" dilutions="" should="" be="" determined="" by="" each="" laboratory="" for="" each="">
• Molecular Mass: 45 KDa (monomer)
• AA Sequence: Ser21-Thr189
• Endotoxin: <0.06 eu/μg="" as="" determined="" by="" lal="" test.="">
• Purity: >98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: HAVCR2
• Official Symbol: HAVCR2
• Synonyms: Tim3; TIM-3; Timd3; Havcr2
• Gene ID: 171285
• mRNA Refseq: NM_134250
• Protein Refseq: NP_599011
• UniProt ID: Q8VIM0
• Chromosome Location: 11 B1.1; 11
• Function: protein binding