Active Recombinant Human HAVCR2 Protein, His-Avi-tagged, Biotinylated

Cat.No. : HAVCR2-705H
Product Overview : Biotinylated Human TIM-3 / HAVCR2, His Tag is expressed from HEK293 cells. It contains AA Ser 22 - Arg 200 (Accession # Q8TDQ0-1). This protein carries an Avi tag at the C-terminus, followed by a polyhistidine tag.
Availability March 14, 2025
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Species : Human
Source : HEK293
Tag : Avi&His
Protein Length : 22-200 a.a.
Predicted N Terminal : Ser 22
Form : Lyophilized from 0.22 um filtered solution in PBS, pH7.4, 10% trehalose.
Bio-activity : Immobilized Anti-TIM3 MAb, Human IgG4 at 2 ug/mL (100 uL/well) can bind Biotinylated Human TIM-3, His Tag with a linear range of 0.4-13 ug/mL.
Molecular Mass : The protein has a calculated MW of 23.1 kDa. The protein migrates as 45-55 kDa under reducing condition (SDS-PAGE) due to glycosylation.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >90% as determined by SDS-PAGE.
Characteristic : Biotinylation of this product is performed using Avitag technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin. The biotin to protein ratio is 0.5-1 as determined by the HABA assay.
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : For long term storage, the product should be stored at lyophilized state at -20ºC or lower. Please avoid repeated freeze-thaw cycles. No activity loss is observed after storage at: 4-8ºC for 12 months in lyophilized state; -70ºC for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name HAVCR2 hepatitis A virus cellular receptor 2 [ Homo sapiens ]
Official Symbol HAVCR2
Synonyms HAVCR2; hepatitis A virus cellular receptor 2; FLJ14428; Tim 3; TIM3; TIMD3; kidney injury molecule-3; T-cell membrane protein 3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain-containing protein 3; KIM-3; Tim-3; TIMD-3; HAVcr-2;
Gene ID 84868
mRNA Refseq NM_032782
Protein Refseq NP_116171
MIM 606652
UniProt ID Q8TDQ0

Not For Human Consumption!

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