Active Recombinant Human HAVCR1, HIgG1 Fc-tagged
Cat.No. : | HAVCR1-2312H |
Product Overview : | The extracellular domain of human Tim-1 (NP_036338.2) (Ser21-Gln295) is fused to the N-terminus of the Fc region of human IgG1 was expressed in CHO cell. |
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Species : | Human |
Source : | CHO |
Tag : | Fc |
Description : | The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. Theencoded protein may be involved in the moderation of asthma and allergic diseases. The reference genomerepresents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAVseropositive individuals. Three transcript variants encoding the same protein have been found for this gene |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated human T cells. |
Molecular Mass : | 57 KDa (monomer) |
AA Sequence : | Ser21-Gln295 |
Endotoxin : | <0.06 eu/μg="" as="" determined="" by="" lal="" test.="">0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name | HAVCR1 hepatitis A virus cellular receptor 1 [ Homo sapiens ] |
Official Symbol | HAVCR1 |
Synonyms | HAVCR1; hepatitis A virus cellular receptor 1; HAVCR; HAVCR 1; TIM 1; TIM1; TIMD1; kidney injury molecule 1; T-cell membrane protein 1; T cell immunoglobin domain and mucin domain protein 1; TIM; KIM1; KIM-1; TIM-1; TIMD-1; HAVCR-1; |
Gene ID | 26762 |
mRNA Refseq | NM_001099414 |
Protein Refseq | NP_001092884 |
MIM | 606518 |
UniProt ID | Q96D42 |
Chromosome Location | 5q33.2 |
Function | receptor activity; |
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Not For Human Consumption!
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