Active Recombinant Human GPNMB, Fc Chimera

Source :	Mammalian cells
Species :	Human
Tag :	Fc
Predicted N Terminal :	Lys23
Form :	Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity :	Measured by the ability of the immobilized protein to induce pro-MMP-9 secretion by NHLF human normal lung fibroblastsThe ED50 for this effect is typically 2.5 - 10 µg/mL. Optimal dilutions should be determined by each laboratory for each application.
Molecular Mass :	Recombinant Human GPNMB, Fc Chimera has a calculated MW of 78.6 kDa (monomer). In SDS-PAGE migrates as 115-125 kDa, reducing conditions.
Purity :	>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage :	Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Name	GPNMB glycoprotein (transmembrane) nmb [ Homo sapiens ]
Official Symbol	GPNMB
Synonyms	GPNMB; glycoprotein (transmembrane) nmb; transmembrane glycoprotein NMB; glycoprotein NMB; glycoprotein nmb like protein; HGFIN; NMB; osteoactivin; transmembrane glycoprotein; glycoprotein nmb-like protein; transmembrane glycoprotein HGFIN;
Gene ID	10457
mRNA Refseq	NM_001005340
Protein Refseq	NP_001005340
MIM	604368
UniProt ID	Q14956
Chromosome Location	7p