Active Recombinant Human GPC3, Fc-tagged, Biotinylated
| Cat.No. : | GPC3-619H |
| Product Overview : | The recombinant human GPC3 extracellular or ecto-domain (ECD) is expressed as a 762 amino acid protein consisting of Gln25-Val558 region of GPC3 (Uniprot accession# P51654-3) and a C-terminal Fc fusion from human IgG1, which exists as multiple proteolytically processed species under reducing conditions. |
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| Source : | Human cells |
| Species : | Human |
| Tag : | Fc |
| Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier and preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule). |
| Bio-activity : | Binds human FGF-basic/FGF2 in a functional ELISA. |
| Molecular Mass : | Calculated molecular mass (kDa): 86.2; Estimated by SDS-PAGE under reducing condition (kDa): 3 major bands at 40, 60 and 95-125 kDa. |
| Endotoxin : | <0.1 eu="" per="" 1="" μg="" of="" purified="" recombinant="" protein="" determined="" by="" the="" lal=""> |
| Purity : | >90% judged by SDS-PAGE under reducing condition |
| Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
| Protein length : | 25-558 a.a. |
| Gene Name | GPC3 glypican 3 [ Homo sapiens ] |
| Official Symbol | GPC3 |
| Synonyms | GPC3; glypican 3; SDYS; glypican-3; DGSX; glypican proteoglycan 3; OCI 5; SGB; SGBS; SGBS1; secreted glypican-3; intestinal protein OCI-5; heparan sulphate proteoglycan; MXR7; OCI-5; GTR2-2; |
| Gene ID | 2719 |
| mRNA Refseq | NM_001164617 |
| Protein Refseq | NP_001158089 |
| MIM | 300037 |
| UniProt ID | P51654 |
| Chromosome Location | Xq26 |
| Pathway | Glypican 3 network, organism-specific biosystem; Glypican pathway, organism-specific biosystem; |
| Function | heparan sulfate proteoglycan binding; peptidyl-dipeptidase inhibitor activity; protein binding; |
Not For Human Consumption!
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