Active Recombinant Human FGF8 Protein, Animal Free

• Cat.No.: FGF8-12H
• Product Overview: Recombinant Human FGF8 Protein without tag was expressed in Human cells.
  Animal Free and Xeno Free

Specification

• Species: Human
• Source: Human Cells
• Description: FGF-8b(FGF-8) is belonging to the FGF family, which is widely expressed during embryogenesis. There are four known alternate spliced forms of FGF-8: FGF-8a, FGF-8b, FGF-8e and FGF-8f. Proteins of this family play an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. FGF-8b is required for normal brain, eye, ear and limb development during embryogenesis. It is also required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-8b shows the strongest receptor affinity and oncogenic transforming capacity.
• Bio-activity: The activity was measured by its ability to stimulate the proliferation of 3T3 mouse fibroblast cells.
• Molecular Mass: 35-45 kDa
• Endotoxin: <0.5 EU/ μg
• Purity: High Purity, >95% by SDS-PAGE
• Stability: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -80 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS without carrier protein
• Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Gene Information

• Gene Name: FGF8 fibroblast growth factor 8 [ Homo sapiens (human) ]
• Official Symbol: FGF8
• Synonyms: FGF8; fibroblast growth factor 8; HH6; AIGF; KAL6; FGF-8; HBGF-8; fibroblast growth factor 8; androgen-induced growth factor; fibroblast growth factor 8 (androgen-induced); heparin-binding growth factor 8
• Gene ID: 2253
• mRNA Refseq: NM_033163
• Protein Refseq: NP_149353
• MIM: 600483
• UniProt ID: P55075