Active Recombinant Human CXCL11 protein, Tag Free, Alexa Fluor 647 labeled
Cat.No. : | CXCL11-280H-AF647 |
Product Overview : | E. coli expressed Human CXCL11 protein was labeled with AF647 in vitro. |
Availability | March 31, 2025 |
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Species : | Human |
Source : | E.coli |
Tag : | Non |
Protein Length : | 22-94 aa |
Description : | CXCL11 also known as I-TAC is belonging to the CXC chemokine family and shares 36 % and 37 % amino acid sequence homology with IP-10 and MIG, respectively. It is highly expressed in peripheral blood leukocytes, pancreas and liver. Expression of CXCL11 is strongly induced by IFN-γ and IFN-β, and weakly induced by IFN-α. This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3, which with a higher affinity than do the other chemokines for this receptor, CXCL9 and CXCL10. Similar to CXCL10, CXCL11 has been shown to be a chemoattractant for IL-2-activated T-lymphocytes, but not for isolated T-cells, neutrophils or monocytes. |
Tag : | Non |
Conjugation/Label : | Alexa Fluor 647 labeled |
Form : | Solution |
Bio-activity : | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human IL-2 activated human T-lymphocytes is in a concentration range of 0.1-10 ng/ml. |
Molecular Mass : | 8.3 kDa |
AA Sequence : | FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF |
Purity : | >97% by SDS-PAGE and HPLC analysis |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied |
Concentration : | 2.0 mg/mL |
Gene Name | CXCL11 C-X-C motif chemokine ligand 11 [ Homo sapiens (human) ] |
Official Symbol | CXCL11 |
Synonyms | CXCL11; chemokine (C-X-C motif) ligand 11; SCYB9B, SCYB11, small inducible cytokine subfamily B (Cys X Cys), member 11; C-X-C motif chemokine 11; b R1; H174; I TAC; IP 9; beta-R1; small inducible cytokine B11; small-inducible cytokine B11; interferon gamma-inducible protein 9; interferon-inducible T-cell alpha chemoattractant;small inducible cytokine subfamily B (Cys-X-Cys), member 11; small inducible cytokine subfamily B (Cys-X-Cys), member 9B; IP9; IP-9; b-R1; I-TAC; SCYB11; SCYB9B;MGC102770 |
Gene ID | 6373 |
mRNA Refseq | NM_005409 |
Protein Refseq | NP_005400 |
MIM | 604852 |
UniProt ID | O14625 |
◆ Recombinant Proteins | ||
CXCL11-280H-AF647 | Active Recombinant Human CXCL11 protein, Tag Free, Alexa Fluor 647 labeled | +Inquiry |
CXCL11-20H | Recombinant Human CXCL11 Protein, Biotin-tagged | +Inquiry |
CXCL11-167H | Active Recombinant Human Chemokine (C-X-C Motif) Ligand 11, MIgG2a Fc-tagged | +Inquiry |
CXCL11-931R | Recombinant Rhesus Macaque CXCL11 Protein, His (Fc)-Avi-tagged | +Inquiry |
CXCL11-39M | Recombinant Mouse CXCL11 Protein, Biotin-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
CXCL11-7171HCL | Recombinant Human CXCL11 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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