Active Recombinant Human CD200, HIgG1 Fc-tagged
| Cat.No. : | CD200-101H |
| Product Overview : | The extracellular domain of human CD200 (AAH31103.1)(Gln31-Ser236) is fused to the N-terminus of the Fc region of human IgG1was expressed in CHO cell |
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| Description : | The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene |
| Source : | CHO cells |
| Species : | Human |
| Tag : | HIgG1 Fc-tagged |
| Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
| Bio-activity : | Measured by its binding ability in a functional ELISA. |
| Molecular Mass : | 48KDa (monomer) |
| AA Sequence : | Gln31-Ser236 |
| Endotoxin : | <0.06 eu/μg="" as="" determined="" by="" lal="" test.=""> |
| Purity : | >98%, by SDS-PAGE under reducing conditions. |
| Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
| Warning : | Avoid freeze/thaw cycles. |
| Protein length : | 31-236 a.a. |
| Gene Name | CD200 CD200 molecule [ Homo sapiens ] |
| Official Symbol | CD200 |
| Synonyms | CD200; CD200 molecule; antigen identified by monoclonal MRC OX 2 , CD200 antigen , MOX1, MOX2; OX-2 membrane glycoprotein; MRC; OX 2; CD200 antigen; MRC OX-2 antigen; antigen identified by monoclonal MRC OX-2; MOX1; MOX2; OX-2; |
| Gene ID | 4345 |
| mRNA Refseq | NM_001004196 |
| Protein Refseq | NP_001004196 |
| MIM | 155970 |
| UniProt ID | P41217 |
| Chromosome Location | 3 |
| Pathway | Adaptive Immune System, organism-specific biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; |
| Function | identical protein binding; protein binding; |
Not For Human Consumption!
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