Active Recombinant Human CCR8 protein

• Cat.No.: CCR8-0184H
• Product Overview: Recombinant Human CCR8 protein(Asp 2 - Leu 355) was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: Non
• Form: The VLPs are highly immunogenic, so the immunization strategy should be optimized (antigen dose, regimen and adjuvant).Supplied as 0.2 μm filtered solution in PBS, Arginine, pH7.4 with trehalose as protectant.
• Bio-activity: Immobilized Human CCR8 Full Length Protein-VLP at 10 μg/mL (100 μL/well) can bind Anti-CCR8 Antibody, Human IgG1 with a linear range of 0.078-2.5 μg/mL.
• Molecular Mass: Virus-like particles(VLPs) are formed by self-assembly of envelop/capsid proteins from viruses. Membrance Proteins can be constituted in-situ with VLPs produced from HEK293 cell cultures. These VLPs concentrate conformationally intact membrane proteins directly on the cell surface and produce soluble, high-concentration proteins perfect for immunization and antibody screening. The VLPs provide the display of properly folded membrane proteins in their native cellular membrane in a compact size of 100~300 nm diameter (similar to the size of most viruses) making it optimal targets for dendritic cells in vivo and surface attachment for phage display.
• Protein length: Asp 2 - Leu 355
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Storage: For long term storage, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: CCR8 chemokine (C-C motif) receptor 8 [ Homo sapiens ]
• Official Symbol: CCR8
• Synonyms: CCR8; chemokine (C-C motif) receptor 8; CMKBR8, CMKBRL2; C-C chemokine receptor type 8; CDw198; CKR L1; CY6; GPR CY6; TER1; CC chemokine receptor 8; chemokine receptor-like 1; chemokine (C-C) receptor 8; CC chemokine receptor CHEMR1; CC-chemokine receptor chemr1; chemokine (C-C) receptor-like 2; CCR-8; CKRL1; CMKBR8; GPRCY6; CMKBRL2; CC-CKR-8; MGC129966; MGC129973
• Gene ID: 1237
• mRNA Refseq: NM_005201
• Protein Refseq: NP_005192
• MIM: 601834
• UniProt ID: P51685