Active Recombinant Human BMPR1B Protein, His & GST-tagged

• Cat.No.: BMPR1B-223H
• Product Overview: Recombinant human ALK6 (NP_001194.1) cytoplasmic domain (Arg 149-Leu 502) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST&His
• Protein Length: 149-502 a.a.
• Predicted N Terminal: Met
• Form: Supplied as sterile 50mM Tris, 100mM NaCl, pH 8.5, 20% gly, 0.3mM DTT.
• Bio-activity: Kinase activity untested
• Molecular Mass: The recombinant human ALK6 (149-502)/GST chimera consists of 591 amino acids and has a calculated molecular mass of 68.3 KDa. It migrates as an approximately 55 KDa band in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >90 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: BMPR1B bone morphogenetic protein receptor type IB [ Homo sapiens ]
• Official Symbol: BMPR1B
• Synonyms: ALK6; AMDD; ALK-6; CDw293; BMP type-1B receptor; BMPR-1B; activin receptor-like kinase 6; bone morphogenetic protein receptor, type IB; serine/threonine receptor kinase
• Gene ID: 658
• mRNA Refseq: NM_001203
• Protein Refseq: NP_001194
• MIM: 603248
• UniProt ID: O00238
• Chromosome Location: 4q22-q24
• Pathway: BMP signaling, organism-specific biosystem; BMP signaling, conserved biosystem; Cytokine-cytokine receptor interaction, conserved biosystem