Active Recombinant Human ANGPTL8 Protein, His-tagged

• Cat.No.: ANGPTL8-01H
• Product Overview: Human Angiopoietin-like Protein 8/Betatrophin (Ala22-Ala198) and Human Fractalkine mucin-like stalk (Phe103-Thr338) with 6-His tag at C-terminus was expressed in Chinese Hamster Ovary cell line.

Specification

• Species: Human
• Source: CHO
• Tag: His
• Protein Length: 22-198
• Description: Predicted to enable hormone activity. Involved in regulation of lipid metabolic process and triglyceride homeostasis. Acts upstream of or within positive regulation of protein processing and regulation of lipoprotein metabolic process. Located in extracellular region.
• Bio-activity: Measured by its binding ability in a functional ELISA. When Recombinant Human Angiopoietin-like Protein 3/ANGPTL3 is immobilized at 1 μg/mL (100 μL/well), the concentration of Recombinant Human Angiopoietin-like Protein 8/Betatrophin that produces 50% of the optimal binding response is 0.15‑1.2 μg/mL.
• Molecular Mass: Predicted Molecular Mass: 45 kDa
  SDS-PAGE: 70-93 kDa, under reducing conditions
• N-terminal Sequence Analysis: Ala22
• Endotoxin: <0.10 EU/μg of the protein by the LAL method.
• Purity: >85%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS, NaCl and CHAPS with Trehalose.
• Reconstitution: Reconstitute at 400 μg/mL in water.
• Shipping: The product is shipped at ambient temperature.

Gene Information

• Gene Name: ANGPTL8 angiopoietin like 8 [ Homo sapiens (human) ]
• Official Symbol: ANGPTL8
• Synonyms: ANGPTL8; angiopoietin like 8; RIFL; TD26; PRO1185; PVPA599; C19orf80; angiopoietin-like protein 8; hepatocellular carcinoma-associated gene TD26; hepatocellular carcinoma-associated protein TD26; lipasin; refeeding-induced fat and liver protein
• Gene ID: 55908
• mRNA Refseq: NM_018687
• Protein Refseq: NP_061157
• MIM: 616223
• UniProt ID: Q6UXH0