Active Recombinant Human ADAM12, His-tagged

• Cat.No.: ADAM12-233H
• Product Overview: Recombinant Human ADAM12 (Accession # AAC08702) Arg29-Ser513, fused with an N-terminal signal peptide and a C-terminal 6-His tag, was produced in Chinese Hamster Ovary cell line, CHO-derived.

Specification

• Species: Human
• Source: CHO
• Tag: His
• Protein Length: 29-513 a.a.
• Predicted N Terminal: Arg29
• Form: Supplied as a 0.2 µm filtered solution in HEPES, NaCl and CaCl2.
• Bio-activity: Measured by its ability to cleave IGFBP-3.
• Molecular Mass: Recombinant Human ADAM12, His-tagged has a calculated MW of 55 kDa (Pro) & 34 kDa (Mature). In SDS-PAGE migrates as 28 kDa, 44 kDa & 68 kDa, reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: ADAM12 ADAM metallopeptidase domain 12 [ Homo sapiens ]
• Official Symbol: ADAM12
• Synonyms: ADAM12; ADAM metallopeptidase domain 12; a disintegrin and metalloproteinase domain 12 (meltrin alpha); disintegrin and metalloproteinase domain-containing protein 12; MCMPMltna; meltrin alpha; MLTN; meltrin-alpha; MCMP; MLTNA
• Gene ID: 8038
• mRNA Refseq: NM_003474
• Protein Refseq: NP_003465
• MIM: 602714
• UniProt ID: O43184
• Chromosome Location: 10q26