Active Recombinant Full Length Mouse HDAC6 Protein, N-GST-tagged

• Cat.No.: HDAC6-35MFL
• Product Overview: Recombinant full-length mouse HDAC6 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: Enables cytoskeletal protein binding activity; protein deacetylase activity; and ubiquitin binding activity. Involved in several processes, including positive regulation of peptidyl-serine phosphorylation; protein deacetylation; and protein destabilization. Acts upstream of or within several processes, including aggresome assembly; cellular protein metabolic process; and neuron projection morphogenesis. Located in several cellular components, including dendrite; microtubule cytoskeleton; and perikaryon. Part of protein-containing complex. Is expressed in several structures, including central nervous system; early embryo; future midbrain; gut gland; and lung. Human ortholog(s) of this gene implicated in chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia. Orthologous to human HDAC6 (histone deacetylase 6).
• Source: Insect cells
• Species: Mouse
• Tag: GST
• Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mMDTT, 25% glycerol.
• Bio-activity: 11,370 RLU/min/ng
• Molecular Mass: Observed MW ~159 kDa.
  Calculated MW ~157 kDa.
• Purity: >90%
• Stability: lyr at -70 centigrade from date of shipment.
• Storage: Store product at -70 centigrade.For optimal storage, aliquot target in to smaller quantities after centrifugation and store at recommended temperature. For most favorable performance,avoid repeated handling and multiplefreeze/thaw cycles.
• Concentration: 0.1 ug/ul

Gene Information

• Gene Name: Hdac6 histone deacetylase 6 [ Mus musculus (house mouse) ]
• Official Symbol: HDAC6
• Synonyms: Hd6; Sfc6; Hdac5; mHDA2
• Gene ID: 15185
• mRNA Refseq: NM_010413.4
• Protein Refseq: NP_034543.3
• UniProt ID: Q9Z2V5