Active Recombinant Full Length Human PTPN2, GST-tagged

• Cat.No.: PTPN2-1519H
• Product Overview: Recombinant full length human PTPN2 was expressed in E. coli cells using a N-terminal GST tag.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-415 a.a.
• Description: Protein tyrosine phosphatase, non-receptor type 2 (PTPN2), is one of the most abundant mammalian tyrosine phosphatase. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. By virtue of protein tyrosine phosphatase activity, PTPN2 is known to be a signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation involved in cell communication and signal transduction.
• Form: Recombinant protein stored in 20 mM MOPS, pH 7.5, 50 mM NaCl, 0.25 mM DTT, 0.1 mM PMSF, 30% glycerol.
• Bio-activity: 8150 nmol/min/mg
• Molecular Mass: ~69 kDa
• Purity: >85%
• Applications: Phosphatase Assay, Western Blot
• Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
• Concentration: 0.1μg/μl

Gene Information

• Gene Name: PTPN2 protein tyrosine phosphatase, non-receptor type 2 [ Homo sapiens ]
• Official Symbol: PTPN2
• Synonyms: PTPN2; protein tyrosine phosphatase, non-receptor type 2; PTPT; tyrosine-protein phosphatase non-receptor type 2; TC PTP; TCELLPTP; TCPTP; T-cell protein tyrosine phosphatase; PTN2; TC-PTP
• Gene ID: 5771
• mRNA Refseq: NM_001207013
• Protein Refseq: NP_001193942
• MIM: 176887
• UniProt ID: P17706
• Chromosome Location: 18p11.3-p11.2
• Pathway: Cytokine Signaling in Immune system, organism-specific biosystem; Immune System, organism-specific biosystem; Interferon Signaling, organism-specific biosystem; Interferon gamma signaling, organism-specific biosystem; Regulation of IFNG signaling, organism-specific biosystem
• Function: hydrolase activity; non-membrane spanning protein tyrosine phosphatase activity; protein binding; protein tyrosine phosphatase activity; protein tyrosine phosphatase activity; receptor activity