Active Recombinant Cynomolgus CTLA4 protein, Fc-tagged

• Cat.No.: CTLA4-8852C
• Product Overview: Recombinant Cynomolgus CTLA4(Met1-Asp161) fused with Fc region of human IgG1 at C-terminal was expressed in HEK293.

Specification

• Species: Cynomolgus
• Source: HEK293
• Tag: Fc
• Protein Length: Met1-Asp161
• Description: CTLA4 played an important role in many functions.
• Predicted N Terminal: Ala 37
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Bio-activity: Measured by its binding ability in a functional ELISA.
  Immobilized human B7-1-His (Cat:10698-H08H) at 10 μg/ml (100 μl/well) can bind Cynomolgus CTLA4-Fc, The EC50 of Cynomolgus CTLA4-Fc is 6.0-14.5 ng/ml.
• Molecular Mass: The recombinant cynomolgus/rhesus CTLA4 is a disulfide-linked homodimer. The reduced monomer comprises 366 amino acids and has a calculated molecular mass of 40.4 KDa.The apparent molecular mass of the protein is approximately 52 KDa respectively in SDS-PAGE.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Stability: Samples are stable for up to twelve months from date of receipt at -70 centigrade.
• Storage: Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
  Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Gene Information

• Gene Name: CTLA4 cytotoxic T-lymphocyte associated protein 4 [ Macaca fascicularis ]
• Official Symbol: CTLA4
• Synonyms: CTLA4; cytotoxic T-lymphocyte associated protein 4
• Gene ID: 102115124