Active Native Human Plasminogen

Description :	Found at 12 mg per 100 ml normal plasma. It is the precursor of the serine protease plasmin which s involved in fibrinolysis.
Source :	Human Plasma
Species :	Human
Form :	Lyophilized
Bio-activity :	>=120 units/mg protein. One unit is de ned as the amount of enzyme which will hydrolyze 1 μmole of N-tosyl-L-arginine methyl ester in 30 minutes at 37°C at pH 8.0.
Molecular Mass :	MW: 90,000 to 92,000
Purity :	>95% by SDS-PAGE
Usage :	For research or further manufacturing use only.
Quality Control Test :	Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Stability :	>1 year
Storage :	<=>
Storage Buffer :	20 mM Tris-HCl, pH 7.5, with 2 mM EDTA
Tag :	Non

Gene Name	PLG plasminogen [ Homo sapiens ]
Official Symbol	PLG
Synonyms	PLG; plasminogen; plasmin; DKFZp779M0222;
Gene ID	5340
mRNA Refseq	NM_001168338
Protein Refseq	NP_001161810
MIM	173350
UniProt ID	P00747
Chromosome Location	6q26
Pathway	Activation of Matrix Metalloproteinases, organism-specific biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; Blood Clotting Cascade, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Degradation of the extracellular matrix, organism-specific biosystem;
Function	apolipoprotein binding; cell surface binding; peptidase activity; protein binding; protein domain specific binding; serine-type endopeptidase activity;