Active GMP Recombinant Human ICOS protein, Fc-tagged

• Cat.No.: ICOS-101HG
• Product Overview: GMP Recombinant Human ICOS protein(NP_036224.1)(354 aa), fused with Fc Tag at the C-terminal, was expressed in HEK293 cell in an animal component free process under cGMP guidelines.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: DNA sequence encoding Human ICOS(NCBI Reference Sequence: NP_036224.1) was expressed with Fc tag at the C-terminal.
• Form: Freeze-dried powder contains Sterile PBS (pH 7.4) with 6% mannitol.
• Bio-activity: The linear range of immobilized Human B7-H2(His tag) at 2ug/mL(100 uL/well) that can bind to ICOS(Fc tag) is 0.2-10ng/mL.
• Molecular Mass: Recombinant Human ICOS protein contains 354 aa. It has a predicted MW of 40.7 kDa.
• Endotoxin: <0.1EU/ug
• Purity: >=95% by SDS-PAGE and HPLC
• Storage: The lyophilized preparation can be stored at 4°C for 24 months, and the dissolved liquid can be stored at -20°C for 6-12 months to avoid repeated freezing and thawing
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: ICOS inducible T-cell co-stimulator [ Homo sapiens ]
• Official Symbol: ICOS
• Synonyms: CD278; AILIM; Inducible T-cell costimulator
• Gene ID: 29851
• mRNA Refseq: NM_012092
• Protein Refseq: NP_036224
• MIM: 604558
• UniProt ID: Q9Y6W8