Active GMP Recombinant Human BMP-2 Protein

• Cat.No.: BMP2-01HG
• Product Overview: Recombinant human BMP2 protein, was expressed in CHO-K1 cell-derived in an animal component free process under cGMP guidelines.

Specification

• Species: Human
• Source: CHO
• Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients
• Form: Lyophilized powder
• Endotoxin: <20 EU/mg
• Bio-activity: >2.0 x 10^4 IU/mg
• Purity: >95.0% by high performance liquid chromatography (SEC-HPLC) and SDS-PAGE.
• Storage Buffer: 10mM Phosphate-Buffered Saline (pH 7.2)
• Storage: Stable storage at 4℃ for 7-10 days; for long-term storage, please store at -20℃ after dispensing.
• Sterility: Sterility
• Instructions: It is recommended that lyophilized GMP rhBMP2 be dissolved in water for injection or sterilized ultrapure water at a concentration of not less than 100 μg/ml, pending further dilution to working concentration.

Gene Information

• Gene Name: BMP2 bone morphogenetic protein 2 [ Homo sapiens (human) ]
• Official Symbol: BMP2
• Synonyms: BDA2; BMP2A; SSFSC; SSFSC1
• Gene ID: 650
• mRNA Refseq: NM_001200.4
• Protein Refseq: NP_001191.1
• UniProt ID: P12643
• MIM: 112261