Ac-DEVD-pNA
Cat.No. : | DYE-123 |
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Tag : | Non |
Description : | During apoptosis, activated caspase-3 cleaves several substrates, including poly (ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD. Ac-DEVD-pNA is a para-nitro aniline chromophore cleaved by caspases (Km = 18, 11, 32, 180, and 12 μM for caspases-1, -3, -4, -6, and -7, respectively). It is not cleaved by caspase-2. Cleavage is monitored colorimetrically at 405 nm. |
Molecular Mass : | 638.58 |
Ex(nm) : | 408 |
Solvent : | DMSO |
Storage : | Store at -20°C in the dark. Dessicated. |
Not For Human Consumption!
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