Ac-DEVD-AFC
Cat.No. : | DYE-120 |
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Description : | During apoptosis, activated caspase-3 cleaves several substrates, including poly (ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD. Ac-DEVD-AFC is a fluorogenic substrate for activated caspase-3 (Km = 9.7 μM), as well as related caspases. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. |
Molecular Mass : | 729.61 |
Ex(nm) : | 351 |
Em(nm) : | 430 |
Solvent : | DMSO |
Storage : | Store at -20°C in the dark. Dessicated. |
Tag : | Non |
Not For Human Consumption!
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