UBE2W
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Official Full Name
ubiquitin-conjugating enzyme E2W (putative) -
Synonyms
UBE2W;ubiquitin-conjugating enzyme E2W (putative);probable ubiquitin-conjugating enzyme E2 W;FLJ11011;hUBC 16;hUBC16;Probable ubiquitin conjugating enzyme E2 W;UBE 2W;UBE2W_HUMAN;Ubiquitin carrier protein W;Ubiquitin conjugating enzyme 16;Ubiquitin conjugating enzyme E2 W;Ubiquitin conjugating enzyme E2W;Ubiquitin protein ligase W;Ubiquitin-protein ligase W;OTTHUMP00000226882;OTTHUMP00000226883;ubiquitin-conjugating enzyme 16;UBC16;hUBC-16
Recombinant Proteins
- Human
- Chicken
- Rhesus macaque
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- Human
- HEK293
- Insect Cell
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- GST
- Non
- His&Strep
- Myc&DDK
- His&SUMO
- His&Fc&Avi
Involved Pathway
UBE2W involved in several pathways and played different roles in them. We selected most pathways UBE2W participated on our site, such as Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2W were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ubiquitin mediated proteolysis | UBE2L3A,CBLB,BIRC2,KEAP1,UBE2G1B,PRPF19,UBE2K,SIAH2L,PPIL2,RBX1 |
Protein Function
UBE2W has several biochemical functions, for example, ATP binding,protein binding,ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2W itself. We selected most functions UBE2W had, and list some proteins which have the same functions with UBE2W. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin protein ligase activity | RAG2,BFAR,WWP2,TRAIP,UBE2C,STUB1,ANKIB1,NEDD4,UBR1,CDC42 |
| ATP binding | ATP2A1L,PNKP,ITPKB,DYRK3,PTK6B,NLRP4,ABCB4,NSFB,STRC,STK40 |
| ubiquitin-protein transferase activity | CMTM2A,TRAF6,FBXO25,ANAPC4,RNF168,UHRF1,TRIM71,RNF181,TRIM21,RNF4 |
| ubiquitin protein ligase binding | CUL4A,HSPA1B,TRIM37,CXCR4,AXIN2,GPR37,DNM1L,UBE2R2,TP53,XRCC5 |
| protein binding | DOT1L,KHDRBS3,NFKBIL2,TEKT5,SFRS9,PCID2,FUCA2,RPL7,MSH3,PSMA7 |
Interacting Protein
UBE2W has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2W here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2W.
PSTPIP1;RNF5;MARCH5;USHBP1;ROPN1;RNF111
Resources
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References
- Vittal, V; Shi, L; et al. Intrinsic disorder drives N-terminal ubiquitination by Ube2w. NATURE CHEMICAL BIOLOGY 11:83-+(2015).
- Vittal, V; Wenzel, DM; et al. Biochemical and Structural Characterization of the Ubiquitin-Conjugating Enzyme UBE2W Reveals the Formation of a Noncovalent Homodimer. CELL BIOCHEMISTRY AND BIOPHYSICS 67:103-110(2013).
