TK1
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Official Full Name
thymidine kinase 1, soluble -
Overview
Thymidine kinase 1, soluble (gene name TK1), is a human thymidine kinase. -
Synonyms
TK1;thymidine kinase 1, soluble;thymidine kinase, cytosolic;thymidine kinase-1;thymidine kinase 1 soluble isoform;TK2
Recombinant Proteins
- Human
- Canine
- Zebrafish
- Chicken
- E.coli
- C-His
- Mammalian Cells
- HEK293
- His
- His&GST
- Flag
- Non
- His&Fc&Avi
Involved Pathway
TK1 involved in several pathways and played different roles in them. We selected most pathways TK1 participated on our site, such as Pyrimidine metabolism,Drug metabolism - other enzymes,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with TK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | B3GNTL2,SGPL1,DGAT1A,GALNTL5,HEXB,NDUFS5,MTHFR,SDS,MTMR1,PYCR1A |
| Drug metabolism - other enzymes | UGT1A6,TK2,UGT1A4,CES1D,PNAT10,UGT1A9,IMPDH2,TPMT,UCK2,UGT5G1 |
| Pyrimidine metabolism | TWISTNB,UMPS,POLR2J3,TK2,CAD,POLR1E,DPYDB,DCTPP1,TXNRD1,POLR2A |
Protein Function
TK1 has several biochemical functions, for example, ATP binding,identical protein binding,nucleoside kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TK1 itself. We selected most functions TK1 had, and list some proteins which have the same functions with TK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | DIS3L2,PPIE,DEF6,SNRNP70,CCT3,RGS19,DMC1,UBE2C,APPL1,PARP1 |
| identical protein binding | CIDEB,HAND2,SH3GL1,GPR50,SLIT2,PPPDE2,EPS15,TYROBP,LRP6,SCUBE1 |
| thymidine kinase activity | TK2 |
| zinc ion binding | RNF34A,MT1A,L3MBTL4,PJA2,ALKBH8,TRAF6,PHF20B,RBCK1,GALT,TRIM109 |
| ATP binding | CDK11A,TTLL10,MYH11A,TTLL9,DGKD,ATP7A,ADCK1,VRK1,ACTA2,PI4KB |
| nucleoside kinase activity | DCK,UCK1,DGUOK,UCK2,UCK2B,UCK2A |
Interacting Protein
TK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TK1.
MAGEA4;GDF9;GAPDH;TP53;APLP1;TLE1;UNC119;TUBB2A;CRMP1
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