SUGT1

  • Official Full Name

    SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)

  • Overview

    This gene is homologous to the yeast gene SGT1, which encodes a protein involved in kinetochore function and required for the G1/S and G2/M transitions. Complementation studies suggest that the human protein has similar functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

  • Synonyms

    SUGT1;SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae);SGT1;suppressor of G2 allele of SKP1 homolog;SGT1B protein;putative 40-6-3 protein;suppressor of G2 allele of SKP1, S. cerevisiae, homolog of

Recombinant Proteins

  • Human
  • Mouse
  • Chicken
  • Rat
  • Insect Cell
  • E.coli
  • Mammalian Cell
  • HEK293
  • HEK293T
  • T7
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi

    Involved Pathway

    SUGT1 involved in several pathways and played different roles in them. We selected most pathways SUGT1 participated on our site, such as Immune System,Inflammasomes,Innate Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with SUGT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    NOD-like receptor signaling pathway IL8L1,MAPK12,PSTPIP1B,NFKBIAB,HSP90B1,Ccl12,NLRC4,CCL5,CASP8,IL-8
    Innate Immune System CLEC4D,POLR3GLA,PELI1,UNC93B1,MYO1C,SIGIRR,TAX1BP1B,TREM1,DEFB116,CD180
    The NLRP3 inflammasome BTR22,BTR02,TXNIPB,TXNIPA,BTR09,PANX1,BTR29,BTR12,PANX1A,BTR30
    Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways CYLD,BTR12,BTR06,BTR16,PANX1,BTR18,BTR22,BTR02,PANX1B,BTR29
    Inflammasomes BTR02,BTR12,BTR29,TXNIPA,TXNIP,Txn1,NLRP3,BTR22,PANX1A,BTR30
    NOD pathway NLRP3,COPS6,PRDM1,NLRP4,NLRP12,AAMP,NLRP7,NLRP2,NLRP10
    Immune System AP1S3A,CRTAM,KLRB1B,TRIM41,BTR09,TRIM56,FCGR1B,ARIH1,TREM1,SIGLEC7

    Protein Function

    SUGT1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SUGT1 itself. We selected most functions SUGT1 had, and list some proteins which have the same functions with SUGT1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding PHLDA1,RRAS2,SCN5A,MGAT5B,CD19,NCOA2,GCH1,PDCD1,PLXDC1,STX19

    Interacting Protein

    SUGT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SUGT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SUGT1.

    sspH2;LRCH4;SKP1;PHLPP1;MAP3K3;BUB3;NR4A1;recJ;2_aha_camp;AIP;HSP90AA1

    Resources

    Research Area

    Inflammasome

    References

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