SGPL1
-
Official Full Name
sphingosine phosphate lyase 1 -
Overview
Sphingosine-1-phosphate lyase 1 is an enzyme that in humans is encoded by the SGPL1 gene. -
Synonyms
SGPL1;sphingosine phosphate lyase 1;sphingosine-1-phosphate lyase 1;FLJ13811;hSPL;KIAA1252;S1PL;SGPL 1;SGPL1_HUMAN;SP lyase;SP-lyase 1;Sphingosine 1 phosphate aldolase;Sphingosine 1 phosphate lyase 1;Sphingosine-1-phosphate aldolase;SPL 1;SPL;mSPL;OTTMUSP00000042252;OTTMUSP00000042253;OTTMUSP00000042256;AI428538;D10Xrf456
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rat
- Zebrafish
- E.coli
- Mammalian Cell
- Sf9 Insect Cell
- E.coli expression system
- HEK293
- HEK293T
- Mammalian cells
- His
- His&T7
- Non
- His&Fc&Avi
- Myc&DDK
- Flag
Involved Pathway
SGPL1 involved in several pathways and played different roles in them. We selected most pathways SGPL1 participated on our site, such as Sphingolipid metabolism,Metabolic pathways,Sphingolipid signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGPL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Sphingolipid signaling pathway | HRAS,PIK3CB,PLCB2,BID,LASS2,PIK3R3,SGMS1,SPHK1,MAPK12,PIK3CA |
| Sphingolipid metabolism | GALC,PPAP2A,COL4A3BP,SGMS2,ARSE,SMPD2,ARSI,SPTLC2B,SGMS1,B4GALT6 |
| Metabolic pathways | CYP19A1A,ALG3,Akr1b3,RDH8,NADK2,B4GALT4,PRPS1B,GART,PIGL,CHKB |
Protein Function
SGPL1 has several biochemical functions, for example, carboxy-lyase activity,protein binding,pyridoxal phosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SGPL1 itself. We selected most functions SGPL1 had, and list some proteins which have the same functions with SGPL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carboxy-lyase activity | URAD,PDXDC1,ECHDC1,PDXDC2P,BCKDHB,LOC650128,BCKDHA,MVDA,GAD1B,AMD2 |
| protein binding | HIF1A,CACNA1SB,GSDMD,HBA2,CREBZF,UNKL,PFDN2,HOOK3,HBB,SYVN1 |
| pyridoxal phosphate binding | GPT2L,ACCS,LOC650128,AADAT,CBSA,SPTLC2B,THNSL2,AGXT2L2,GOT1L1,GOT2A |
Interacting Protein
SGPL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SGPL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SGPL1.
TMEM173;compound_31;TMBIM4;midostaurin;ssrna_ug;EGFR;ERBB2;vpu;RPL10;IQCB1;PKN2
Resources
Related Services
Related Products
References
- Bode, C; Sensken, SC; et al. Erythrocytes Serve as a Reservoir for Cellular and Extracellular Sphingosine 1-Phosphate. JOURNAL OF CELLULAR BIOCHEMISTRY 109:1232-1243(2010).
