SERPINB2
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Official Full Name
Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 2 -
Overview
Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. -
Synonyms
SERPINB2;serpin peptidase inhibitor, clade B (ovalbumin), member 2;PAI;PAI2;PAI-2;PLANH2;HsT1201;plasminogen activator inhibitor 2;serpin B2;monocyte Arg-serpin;urokinase inhibitor;placental plasminogen activator inhibitor;plasminogen activator inhibitor, type II (arginine-serpin);serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2;OTTHUMP00000066997
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Insect Cells
- Mammalian Cell
- Insect Cell
- E. coli
- Yeast
- HEK293
- Mammalian cells
- HEK293T
- GST
- His
- Non
- His&T7
- His&Fc&Avi
- Myc&DDK
- Flag
- His&SUMO
Involved Pathway
SERPINB2 involved in several pathways and played different roles in them. We selected most pathways SERPINB2 participated on our site, such as Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SERPINB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Amoebiasis | LAMA2,NOS2,LAMC3,RAB7A,C8B,PLCB4,PIK3R3,LAMA3,RELA,PRKCG |
Protein Function
SERPINB2 has several biochemical functions, for example, serine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SERPINB2 itself. We selected most functions SERPINB2 had, and list some proteins which have the same functions with SERPINB2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| serine-type endopeptidase inhibitor activity | SERPINA3K,SPINK1,APP,SPINK11,SPINK6,Serpina1b,SERPINB9,MUG1,AGT,SERPINE1 |
Interacting Protein
SERPINB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SERPINB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SERPINB2.
GABARAPL1
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References
- Palacios, BS; Estrada-Capetillo, L; et al. Macrophages from the synovium of active rheumatoid arthritis exhibit an activin A-dependent pro-inflammatory profile. JOURNAL OF PATHOLOGY 235:515-526(2015).
- King, KE; Reddi, DM; et al. Dysregulated Delta Np63 alpha Negatively Regulates the Maspin Promoter in Keratinocytes Via Blocking Endogenous p73 Binding. MOLECULAR CARCINOGENESIS 53:698-710(2014).
