RHOD
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Official Full Name
ras homolog family member D -
Overview
Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. -
Synonyms
RHOD;ras homolog family member D;ARHD, ras homolog gene family, member D;rho-related GTP-binding protein RhoD;Rho;Rho related GTP binding protein RhoD;Rho related protein HP1;RhoHP1;ras homolog D;Rho-related protein HP1;ras homolog gene f
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Myc
- His&Fc&Avi
Involved Pathway
RHOD involved in several pathways and played different roles in them. We selected most pathways RHOD participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with RHOD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Axon guidance | RASGEF1A,EGF,SEMA6B,CDK5,COL9A3,NRG2A,SLIT2,SRGAP1,MAPK1,MYL12A |
Protein Function
RHOD has several biochemical functions, for example, GTP binding,GTPase activity,protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RHOD itself. We selected most functions RHOD had, and list some proteins which have the same functions with RHOD. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP binding | SCG5,DNAJC27,TRIM66,TUBB4A,RAB9A,RAB20,RAB11BA,IFT27,RNF112,RAP1AA |
| GTPase activity | RND3,GNAV1,GNAI3,GNL1,GNA15.4,MXA,RAB11A,RRAS,GNG10,RAB10 |
| protein kinase binding | AXIN2,PRKAG2,PTEN,TSACC,CCND3,NEFH,PRKAB1,ATF2,DUSP3,RPS6 |
Interacting Protein
RHOD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RHOD here. Most of them are supplied by our site. Hope this information will be useful for your research of RHOD.
DIAPH1;DAAM1;PLXNB1;DAPK3;IHH;ADCK5
RHOD Related Signal Pathway
Resources
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References
- Matsuzaki, H; Fujimoto, T; et al. Tespa1 is a novel component of mitochondria-associated endoplasmic reticulum membranes and affects mitochondrial calcium flux. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 433:322-326(2013).
- Zhang, N; Kolesnikov, AV; et al. Autosomal recessive retinitis pigmentosa E150K opsin mice exhibit photoreceptor disorganization. JOURNAL OF CLINICAL INVESTIGATION 123:121-137(2013).
