PTGER3
-
Official Full Name
prostaglandin E receptor 3 (subtype EP3) -
Overview
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
PTGER3;prostaglandin E receptor 3 (subtype EP3);prostaglandin E2 receptor EP3 subtype;EP3;prostanoid EP3 receptor;PGE receptor, EP3 subtype;PGE2 receptor EP3 subtype;prostaglandin receptor (PGE-2);prostaglandin E receotor EP3 subtype 3 isoform;EP
Recombinant Proteins
- Human
- Chicken
- Rat
- Sus scrofa (Pig)
- Oryctolagus cuniculus (Rabbit)
- Bovine
- Mus musculus
- E.coli
- Mammalian Cells
- HEK293
- His
- His&GST
- Non
- His&Flag
- His&Fc&Avi
Involved Pathway
PTGER3 involved in several pathways and played different roles in them. We selected most pathways PTGER3 participated on our site, such as Calcium signaling pathway,cAMP signaling pathway,Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTGER3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of lipolysis in adipocytes | PIK3CG,INS2,GNAI3,Adcy4,LOC100328615,PDE3B,AKT1,PTGS1,ABHD5,PTGS2 |
| Calcium signaling pathway | TACR2,PDGFRB,PLCG2,P2RX3,CACNA1G,ADCY2B,ADRA1B,ATP2A1,CALM1B,GNAS |
| Pathways in cancer | TRAF4,TCEB1,RARB,FGF4,FZD5,GNG8,FH1,PGF,MMP9,PLCB3 |
| cAMP signaling pathway | PLN,ORAI1,GNAI1,PDE4D,FFAR2,FXYD1,ATP1B3,GHSR,PTCH1,CALML5 |
| Neuroactive ligand-receptor interaction | AGTR1B,FPR3,P2RX4B,SCTR,FSHB,DRD2A,CHRM5A,LEPR,P2RX5,PRLHR2A |
Protein Function
PTGER3 has several biochemical functions, for example, RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding,prostaglandin E receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PTGER3 itself. We selected most functions PTGER3 had, and list some proteins which have the same functions with PTGER3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding | PPARAA,NR2E3,NR2F5,NR2F1B,NR1D2,NR2F6,RORC,NR5A1,NR4A2B,PPARD |
| prostaglandin E receptor activity | PTGER4A,PTGER1A,PTGER1C,PTGER1B,PTGER4B,PTGER4C,HPGD,PTGER1,PTGER2,PTGER4 |
Interacting Protein
PTGER3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTGER3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PTGER3.
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